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RG 125

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Drug Profile

RG 125

Alternative Names: AZD 4076; RG125

Latest Information Update: 31 Oct 2021

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At a glance

  • Originator AstraZeneca; Regulus Therapeutics
  • Class Antisense oligonucleotides; MicroRNAs
  • Mechanism of Action MIRN103 microRNA inhibitors; MIRN103 microRNA modulators; MIRN107 microRNA inhibitors; MIRN107 microRNA modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis

Most Recent Events

  • 02 Aug 2017 Discontinued - Phase-II for Non-alcoholic fatty liver disease in USA (SC) (AstraZeneca pipeline, August 2017)
  • 02 Aug 2017 Discontinued - Phase-II for Non-alcoholic steatohepatitis in USA (SC) (AstraZeneca pipeline, August 2017)
  • 07 Jul 2017 Phase-II clinical trials in Non-alcoholic fatty liver disease in USA (SC) (AstraZeneca pipeline, July 2017)

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