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Enitociclib - Vincerx Pharma

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Drug Profile

Enitociclib - Vincerx Pharma

Alternative Names: BAY-1251152; VIP-152

Latest Information Update: 18 Nov 2024

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At a glance

  • Originator Bayer
  • Developer Bayer; Vincerx Pharma
  • Class Antineoplastics; Fluorinated hydrocarbons; Organic sulfur compounds; Phenyl ethers; Pyridines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 9 inhibitors; Positive transcriptional elongation factor B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Diffuse large B cell lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Haematological malignancies; Non-Hodgkin's lymphoma
  • Phase I Chronic lymphocytic leukaemia; Richter's syndrome; Solid tumours
  • Preclinical Multiple myeloma

Most Recent Events

  • 12 Nov 2024 Updated efficacy data from a phase I trial inSolid tumours released by Vincerx Pharma
  • 11 Nov 2024 Vincerx Pharma completes a phase I trial in Solid tumours (Late-stage disease, Monotherapy, Second-line therapy or greater) and Non-Hodgkin's lymphoma (Late-stage disease, Monotherapy, Second-line therapy or greater) in USA, Spain and Chile (NCT02635672) ,
  • 05 Apr 2024 Pharmacodynamics data from preclinical trial in Solid tumours presented at the 115th Annual Meeting of the American Association for Research (AACR-2024)

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