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Glecaprevir/pibrentasvir - AbbVie

Drug Profile

Glecaprevir/pibrentasvir - AbbVie

Alternative Names: 2DAA; ABT-493/ABT-530; GLE/PIB; Glecaprevir Hydrate/Pibrentasvir - AbbVie; HCV Next Gen; MAVIRET; MAVYRET; Pibrentasvir/glecaprevir; Pibrentasvir/glecaprevir-Abbvie

Latest Information Update: 08 May 2024

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At a glance

  • Originator AbbVie; Enanta Pharmaceuticals
  • Developer AbbVie
  • Class Antivirals; Aza compounds; Benzimidazoles; Carbamates; Cyclic ethers; Cyclopentanes; Cyclopropanes; Fluorobenzenes; Piperidines; Pyrrolidines; Quinoxalines; Small molecules
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors; Hepatitis C virus NS3 protein inhibitors; Hepatitis C virus NS4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hepatitis C

Most Recent Events

  • 03 Mar 2024 Efficacy and adverse events data from the phase II PURGE-C trial in Hepatitis C presented at the 31st Conference on Retroviruses and Opportunistic Infections 2024 (CROI 2024)
  • 22 Aug 2023 AbbVie in collaboration with National Institute of Allergy and Infectious Diseases (NIAID) completes a phase II PURGE-C trial for Hepatitis C in USA, Puerto Rico and Brazil (NCT04042740)
  • 05 Oct 2022 Launched for Hepatitis C (Treatment-naive, Treatment-experienced) in Canada (PO)
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