Drug Profile

Foliglurax - Lundbeck

Alternative Names: Foliglurax; Foliglurax-Prexton-Therapeutics; PXT-2331; PXT002331

Latest Information Update: 21 Jan 2026

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At a glance

Originator Domain Therapeutics
Developer Lundbeck A/S; Prexton Therapeutics
Class Antiparkinsonians; Morpholines; Pyridines; Small molecules
Mechanism of Action Metabotropic glutamate receptor 4 modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Parkinson's disease

Most Recent Events

13 Jan 2026 Domain Therapeutics is now called Kainova Therapeutics
27 Mar 2020 H. Lundbeck A/S discontinues a phase I trial in healthy volunteers in France
27 Mar 2020 Discontinued - Phase-I for Parkinson's disease (Treatment-experienced) in Sweden (PO)

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