DFP 13318

Drug Profile

DFP 13318

Alternative Names: DFP-13318; PEG-SN-38; PEG-SN-38 conjugates - Prolynx; PLX-0264; PLX-038; Polyethylene-glycol-SN 38-conjugates - ProLynx

Latest Information Update: 16 Apr 2018

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At a glance

  • Originator Prolynx
  • Developer Delta-Fly Pharma
  • Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Polyethylenes; Small molecules
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 10 Apr 2018 Prolynx receives a Notice of allowance for PLX 038 (DFP 13318) in USA
  • 30 May 2017 ProLynx receives patent allownace for cleavable linker technology on hydrogels in USA
  • 18 Mar 2016 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT02646852)
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