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IONIS HBV LRx

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Drug Profile

IONIS HBV LRx

Alternative Names: GSK 3389404; GSK-404; IONIS-HBV-LRX; ISIS GSK6 LRx

Latest Information Update: 28 Sep 2022

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer GSK
  • Class Antisense elements; Antisense oligonucleotides; Antivirals
  • Mechanism of Action RNA interference; Viral protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Hepatitis B

Most Recent Events

  • 28 Sep 2022 No development reported - Phase-II for Hepatitis B in China, Japan, South Korea, Philippines, Singapore, Hong Kong (SC) (NCT03020745)
  • 08 Nov 2019 Efficacy, adverse events and pharmacokinetics data from a phase II trial in Hepatitis B presented at the 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2019)
  • 06 Nov 2019 GlaxoSmithKline completes a phase-II clinical trials in Hepatitis B in Singapore, Philippines, South Korea, Japan, China, Hong Kong (SC) (NCT03020745)

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