Troriluzole - Biohaven Pharmaceutical

Drug Profile

Troriluzole - Biohaven Pharmaceutical

Alternative Names: BHV-4157; FC 4157; trigriluzole; Trigriluzole-Biohaven Pharmaceutical; Troriluzole-hydrochloride

Latest Information Update: 26 Jul 2018

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At a glance

  • Originator Yale University
  • Developer Biohaven Pharmaceutical Holding Company; National Cancer Institute (USA); Rutgers Cancer Institute of New Jersey
  • Class Antidementias; Antineoplastics; Benzothiazoles; Neuroprotectants; Small molecules
  • Mechanism of Action Glutamate modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinocerebellar degeneration
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Spinocerebellar degeneration
  • Phase II/III Alzheimer's disease; Obsessive-compulsive disorders
  • Phase I Lymphoma; Solid tumours

Most Recent Events

  • 24 Jul 2018 Phase-II/III clinical trials in Alzheimer's disease in USA (PO) (NCT03605667)
  • 24 Jul 2018 The US FDA approves IND application for a phase II/III trial in Alzheimer’s disease, prior to July 2018
  • 11 Jul 2018 Chemical structure information added
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