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Pifusertib - Taiho Pharmaceutical

Drug Profile

Pifusertib - Taiho Pharmaceutical

Alternative Names: TAS-117

Latest Information Update: 19 Oct 2023

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At a glance

  • Originator Taiho Pharmaceutical
  • Developer Taiho Pharmaceutical; Yonsei University
  • Class Antineoplastics; Imidazoles; Oxazines; Pyridines; Small molecules
  • Mechanism of Action Proto oncogene protein c-akt inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 06 Oct 2023 Taiho Oncology terminates a phase II trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) due to an insufficient rate of accrual of patients (NCT04770246) (EudraCT2020-004770-22)
  • 28 Aug 2023 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease) in Japan (PO)
  • 09 Sep 2022 Efficacy, adverse events and pharmacodynamics data from a phase II trial in Solid tumours presented at the 47th European Society for Medical Oncology Congress (ESMO-2022)
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