Pifusertib - Taiho Pharmaceutical
Alternative Names: TAS-117Latest Information Update: 19 Oct 2023
At a glance
- Originator Taiho Pharmaceutical
- Developer Taiho Pharmaceutical; Yonsei University
- Class Antineoplastics; Imidazoles; Oxazines; Pyridines; Small molecules
- Mechanism of Action Proto-oncogene protein c-akt inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Solid tumours
Most Recent Events
- 06 Oct 2023 Taiho Oncology terminates a phase II trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) due to an insufficient rate of accrual of patients (NCT04770246) (EudraCT2020-004770-22)
- 28 Aug 2023 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease) in Japan (PO)
- 09 Sep 2022 Efficacy, adverse events and pharmacodynamics data from a phase II trial in Solid tumours presented at the 47th European Society for Medical Oncology Congress (ESMO-2022)