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ONCT 216

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Drug Profile

ONCT 216

Alternative Names: I-036; SPH-8216; TK-216

Latest Information Update: 28 Mar 2023

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At a glance

  • Originator Tokalas, Inc.
  • Developer Oncternal Therapeutics, Inc.; Shanghai Pharmaceuticals Holding
  • Class Antineoplastics; Chlorinated hydrocarbons; Cyclopropanes; Indoles; Small molecules
  • Mechanism of Action Proto-oncogene protein c-ets inhibitors; Proto-oncogene protein c-fli-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ewing's sarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ewing's sarcoma
  • Preclinical Diffuse large B cell lymphoma; Prostate cancer
  • No development reported Acute myeloid leukaemia; Glioblastoma

Most Recent Events

  • 28 Mar 2023 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (Parenteral)
  • 28 Mar 2023 No recent reports of development identified for preclinical development in Diffuse large B cell lymphoma in USA (Parenteral)
  • 28 Mar 2023 No recent reports of development identified for preclinical development in Glioblastoma in USA (Parenteral)

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