Drug Profile

PG 101

Alternative Names: PG-101; Pro-ocular^TM

Latest Information Update: 02 Apr 2025

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At a glance

Originator Glia LLC.
Developer Glia LLC.; Ora Inc; PharmaDax; Rhodes Pharmaceuticals
Class Eye disorder therapies
Mechanism of Action Immunomodulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Dry eyes; Graft-versus-host disease

Most Recent Events

18 Mar 2025 Efficacy and adverse event data from a phase II trial in Graft-versus-host disease released by signal12
18 Mar 2025 Signal12 plans a phase III trial for Graft-versus-host disease (Ophthalmic)
13 Aug 2024 Pro-ocular^TM licensed to Signal12

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