Efprezimod alfa - Merck & Co
Alternative Names: CD24-Fc; CD24-Fc-IgG; CD24Fc-fusion protein; MK-7110; Recombinant CD24 IgG1 Fc fusion protein; Recombinant human CD24FcIgLatest Information Update: 22 Apr 2022
Price :
$50 *
At a glance
- Originator OncoImmune
- Developer National Institute of Neurological Disorders and Stroke; OncoImmune
- Class Antineoplastics; Antivirals; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins
- Mechanism of Action Alarmin inhibitors; SIGLEC10 protein stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Autoimmune disorders; COVID 2019 infections; Dyslipidaemias; Graft-versus-host disease; Solid tumours
Most Recent Events
- 22 Apr 2022 University of California, Davis in collaboration with OncoImmune and National Cancer Institute terminates a phase I/II TIRAEC trial in Solid tumors (Late-stage disease, Second-line therapy or greater) in USA because of change in sponsor (NCT04552704)
- 05 Nov 2021 Merck Sharp & Dohme terminates the phase III CATHY trial for Graft-versus-host disease (Prevention) in USA (IV)(NCT04095858)
- 05 Nov 2021 Merck Sharp & Dohme terminates the phase III CATHY trial for Graft-versus-host disease (Prevention) in USA (IV)(NCT04976699)