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CN 105

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Drug Profile

CN 105

Alternative Names: Ac-VSRRR-NH2; CN-105

Latest Information Update: 27 Sep 2024

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At a glance

  • Originator CereNova; Duke University
  • Developer AegisCN; Beijing Tian Tan Hospital; Duke University
  • Class Anti-inflammatories; Antihaemorrhagics; Apolipoprotein therapeutics; Behavioural disorder therapies; Neuropeptides; Neuroprotectants; Nootropics; Peptides; Small molecules
  • Mechanism of Action Apolipoprotein E agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cerebral haemorrhage; Cognition disorders; Delirium

Most Recent Events

  • 28 Jul 2024 Efficacy and adverse event data from the phase II MARBLE trial in Cognition disorders and Delirium presented at the Alzheimer's Association International Conference 2024 (AAIC-2024)
  • 15 Feb 2022 No development reported - Phase-II for Cerebral haemorrhage in USA (IV)
  • 30 Jun 2019 AegisCN completes a phase II trial in Cerebral haemorrhage in USA (NCT03168581)

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