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HTL 18318

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Drug Profile

HTL 18318

Alternative Names: HTL 0018318; HTL18318

Latest Information Update: 02 Apr 2024

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At a glance

  • Originator Heptares Therapeutics
  • Developer AbbVie; Nxera Pharma
  • Class Antidementias; Antipsychotics; Nootropics; Small molecules
  • Mechanism of Action Muscarinic M1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Suspended Alzheimer's disease; Cognition disorders; Dementia

Most Recent Events

  • 31 Mar 2024 Sosei Heptares is now called Nxera Pharma
  • 15 Feb 2022 No development reported - Phase-II for Dementia in Japan (PO)
  • 22 Nov 2021 HTL 18318 licensed to Neurocrine Biosciences worldwide except Japan

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