HTL 18318

Drug Profile

HTL 18318

Alternative Names: HTL 0018318; HTL18318

Latest Information Update: 09 Mar 2018

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At a glance

  • Originator Heptares Therapeutics
  • Developer Allergan; Heptares Therapeutics
  • Class Antidementias; Antipsychotics; Nootropics; Small molecules
  • Mechanism of Action Muscarinic M1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Alzheimer's disease; Cognition disorders

Most Recent Events

  • 10 Nov 2017 Phase-Ib clinical trials in Alzheimer's disease (Adjunctive therapy, In adults, In the elderly) in Spain, Slovakia, Poland, Czech Republic (unspecified route) (NCT03456349)
  • 09 Nov 2017 Sosei Group Corporation plans a phase II proof-of-concept study of HTL 18318 for Dementia with Lewy bodies (Monotherapy) in Japan in 2018 (Trial profile 700267790)
  • 20 Aug 2017 Heptares Therapeutics completes a phase I trial in Healthy volunteers in United Kingdom (PO) (NCT03198624)
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