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Dalpiciclib - Jiangsu Hengrui Medicine Co

Drug Profile

Dalpiciclib - Jiangsu Hengrui Medicine Co

Alternative Names: AiRuiKang; SHR-6390

Latest Information Update: 09 Nov 2022

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Atridia; Jiangsu Hengrui Medicine Co.; Peking University; Shanghai Jiaotong University School of Medicine; Sheng Jing Hospital; Tianjin University
  • Class 2 ring heterocyclic compounds; Amines; Antineoplastics; Cyclopentanes; Ketones; Piperidines; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HER2 negative breast cancer
  • Phase II Breast cancer; HER2 positive breast cancer
  • Phase I/II Malignant melanoma
  • Phase I Solid tumours
  • Phase 0 Head and neck cancer
  • No development reported Gastric cancer

Most Recent Events

  • 09 Sep 2022 Adverse events and efficacy data from a phase III DAWNA-2 trial in Breast cancer presented at the 47th European Society for Medical Oncology Congress (ESMO-2022)
  • 09 Sep 2022 Efficacy and adverse events data from a phase 0 trial in Head and neck cancer (Inoperable/Unresectable, Recurrent, Metastatic disease, Second-line therapy or greater) presented at the 47th European Society for Medical Oncology Congress (ESMO-2022)
  • 09 Sep 2022 Updated efficacy and safety data from a phase III DAWNA-1 trial in advanced breast cancer presented at the 47th European Society for Medical Oncology Congress (ESMO Breast-2022)
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