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Dalpiciclib - Jiangsu Hengrui Medicine Co

Drug Profile

Dalpiciclib - Jiangsu Hengrui Medicine Co

Alternative Names: AiRuiKang; Dalpiciclib Isethionate - Jiangsu Hengrui Medicine Co; SHR-6390

Latest Information Update: 30 Oct 2023

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Atridia; Jiangsu Hengrui Medicine Co.; Peking University; Shanghai Jiaotong University School of Medicine; Sheng Jing Hospital; Tianjin University
  • Class 2 ring heterocyclic compounds; Amines; Antineoplastics; Cyclopentanes; Ketones; Piperidines; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HER2 negative breast cancer
  • Phase II Breast cancer; HER2 positive breast cancer
  • Phase I/II Malignant melanoma
  • Phase I Solid tumours
  • No development reported Gastric cancer; Head and neck cancer

Most Recent Events

  • 25 Oct 2023 Jiangsu HengRui Medicine plans a phase Ib/III trial for Prostate cancer (Metastatic disease; Combination therapy) (PO, Capsule) (NCT06099990)
  • 30 Jul 2023 Jiangsu HengRui Medicine Co. completes a phase-I/II clinical trials in Her2 negative Breast cancer (Combination therapy, First-line therapy, Late-stage disease, Recurrent, Metastatic disease) in China (PO) (NCT03481998)
  • 15 Jun 2023 Jiangsu HengRui Medicine terminates Phase-I trial in HER2 negative breast cancer (Combination therapy, Late-stage disease, Recurrent, Metastatic disease) in China (PO) due to sponsor R & D strategy adjustment (NCT05103826)
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