Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Danicopan - Alexion AstraZeneca Rare Disease

Drug Profile

Danicopan - Alexion AstraZeneca Rare Disease

Alternative Names: 4471; ACH-0144471; ACH-4471; ACH-CFDIS; ALXN 2040; Voydeya

Latest Information Update: 27 Feb 2024

Price : $50 *
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Achillion Pharmaceuticals
  • Developer Achillion Pharmaceuticals; Alexion AstraZeneca Rare Disease
  • Class Amides; Anti-inflammatories; Antianaemics; Eye disorder therapies; Halogenated hydrocarbons; Indazoles; Pyridines; Pyrimidines; Pyrrolidines; Small molecules
  • Mechanism of Action Complement factor D inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Membranoproliferative glomerulonephritis; Paroxysmal nocturnal haemoglobinuria
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Paroxysmal nocturnal haemoglobinuria
  • Phase II Dry macular degeneration
  • Discontinued Haemolytic uraemic syndrome; Membranoproliferative glomerulonephritis

Most Recent Events

  • 26 Feb 2024 CHMP of the EMA recommends approval of Danicopan for Paroxysmal nocturnal haemoglobinuria (Adjunctive treatment)
  • 19 Jan 2024 Registered for Paroxysmal nocturnal haemoglobinuria (Adjunctive treatment) in Japan (PO) - First global approval
  • 16 Jan 2024 Alexion Pharmaceuticals completes the phase III ALPHA trial in Paroxysmal nocturnal haemoglobinuria (Adjunctive treatment) in US, Brazil, Canada, Czechia, France, Germany, Greece, Israel, Italy, Japan, South Korea, Malaysia, Poland, Spain, Taiwan, Thailand and the UK (PO, Tablet)(NCT04469465) (EudraCT2019-003829-18)
Subscriber content

You need to be a logged in subscriber to view this content.

If your organization has a subscription then there are several options available to help you access AdisInsight, even while working remotely.

  • IP authentication when working within your organization’s network.
  • with username/password or try via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days.
  • Contact us at AsktheExpert.AdisInsight@springer.com for assistance.

If your organization does not have a subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Buy a PDF version of the profile.
  • Request a free trial
Back to top