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Verekitug - Upstream Biosciences

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Drug Profile

Verekitug - Upstream Biosciences

Alternative Names: ASP-7266; UPB-101

Latest Information Update: 09 Sep 2025

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At a glance

  • Originator Astellas Pharma
  • Developer Upstream Biosciences
  • Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action CRLF2 protein antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Asthma; Chronic obstructive pulmonary disease; Nasal polyps

Most Recent Events

  • 02 Sep 2025 Adverse events and efficacy data from the phase II VIBRANT trial in Nasal polyps released by Upstream Biosciences
  • 15 Aug 2025 Upstream Bio completes the phase II VIBRANT trial in Nasal polyps (In adults, In the elderly) in USA, Czech Republic, Germany, Poland, Spain (SC) (NCT06164704)
  • 28 Jul 2025 No recent reports of development identified for phase-I development in Asthma in United Kingdom (SC, Injection)

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