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Verekitug - Upstream Biosciences

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Drug Profile

Verekitug - Upstream Biosciences

Alternative Names: ASP-7266; UPB-101

Latest Information Update: 26 Jun 2025

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At a glance

  • Originator Astellas Pharma
  • Developer Upstream Biosciences
  • Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action CRLF2 protein antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Asthma; Nasal polyps; Rhinosinusitis

Most Recent Events

  • 21 May 2025 Upstream Bio initiates a phase II VALOUR trial for Asthma in USA (SC) (NCT06966479)
  • 20 May 2025 Upstream Bio plans a phase IIb trial for Chronic obstructive pulmonary disease (Treatment-experienced) in August 2025 (SC, Injection) (NCT06981078)
  • 06 May 2025 Upstream Bio plans to initiate phase II VALOUR long-term extension study in Asthma in June 2025 (SC, Injection) (NCT06966479)

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