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pegrizeprument - Veloxis Pharmaceuticals

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Drug Profile

pegrizeprument - Veloxis Pharmaceuticals

Alternative Names: Anti CD28 monoclonal antibody - OSE Therapeutics; FR-104; VEL-101

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator Effimune
  • Developer Biomedical Primate Research Center; Janssen Biotech; Nantes University Hospital; OSE Immunotherapeutics; Veloxis Pharmaceuticals
  • Class Anti-inflammatories; Antipsoriatics; Antirheumatics; Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action CD28 antigen inhibitors; T lymphocyte inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Transplant rejection
  • No development reported Encephalomyelitis; Multiple sclerosis; Psoriasis; Rheumatoid arthritis; Uveitis

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Transplant-rejection(In volunteers, In adults) in USA (IV, Injection)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Transplant-rejection(In volunteers, In adults) in USA (SC, Injection)
  • 05 Jun 2024 Adverse events and efficacy data from phase I/II trial in Transplant rejection (In adults, In the elderly) released by company (IV)

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