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Lusvertikimab - OSE Immunotherapeutics

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Drug Profile

Lusvertikimab - OSE Immunotherapeutics

Alternative Names: Anti CD127 monoclonal antibody - OSE Immunotherapeutics; Anti interleukin-7 receptor-α monoclonal antibody - OSE Immunotherapeutics; Effi-7; IL-7 receptor alpha antagonist - OSE Immunotherapeutics; OSE-127; S-95011

Latest Information Update: 17 Mar 2026

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At a glance

  • Originator Effimune
  • Developer OSE Immunotherapeutics; Servier
  • Class Anti-inflammatories; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Interleukin 7 receptor alpha subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Ulcerative colitis
  • No development reported Precursor cell lymphoblastic leukaemia-lymphoma
  • Discontinued Crohn's disease; Sjogren's syndrome; Transplant rejection

Most Recent Events

  • 02 Mar 2026 OSE Immunotherapeutics plans a phase-II trial for Hidradenitis suppurativa (IV)
  • 29 Jan 2026 OSE Immunotherapeutics plans a phase II trial for Pouchitis in the second half of 2026 (IV)
  • 28 Jan 2026 No recent reports of development identified for preclinical development in Precursor-cell-lymphoblastic-leukaemia-lymphoma in France (Parenteral)

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