OSE 127

Drug Profile

OSE 127

Alternative Names: Anti CD127 monoclonal antibody - OSE Immunotherapeutics; Anti interleukin-7 receptor-α monoclonal antibody - OSE Immunotherapeutics; Effi-7; IL-7 receptor antagonist - OSE Immunotherapeutics; Interleukin-7 receptor antagonist - OSE Immunotherapeutics; OSE-127

Latest Information Update: 30 Sep 2017

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At a glance

  • Originator Effimune
  • Developer INSERM; OSE Immunotherapeutics; PX Therapeutics
  • Class Anti-inflammatories; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Interleukin 7 receptor alpha subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Inflammation; Precursor T-cell lymphoblastic leukaemia-lymphoma; Transplant rejection; Ulcerative colitis
  • Research Sjogren's syndrome

Most Recent Events

  • 26 Oct 2017 OSE Immunotherapeutics plans a phase II trial for Ulcerative colitis by end-2018
  • 23 May 2017 OSE Immunotherapeutics extends its agreement with Selexis for clinical development of OSE 127
  • 27 Dec 2016 Effi-7 licensed to Servier Pharmaceuticals worldwide
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