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Daridorexant - Idorsia Pharmaceuticals

Drug Profile

Daridorexant - Idorsia Pharmaceuticals

Alternative Names: ACT-541468; DORA; Nemorexant - Idorsia Pharmaceuticals

Latest Information Update: 12 Nov 2019

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At a glance

  • Originator Actelion Pharmaceuticals
  • Developer Idorsia Pharmaceuticals
  • Class Sleep disorder therapies
  • Mechanism of Action Orexin receptor type 1 antagonists; Orexin receptor type 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Insomnia
  • Phase I Sleep apnoea syndrome

Most Recent Events

  • 22 Oct 2019 Efficacy and adverse events data from pooled analysis of two phase II trials in Insomnia released by Idorsia Pharmaceuticals
  • 10 Oct 2019 Idorsia Pharmaceuticals completes a phase I trial in Healthy volunteers (In adults, In the elderly) in Netherlands (PO, Tablet) (NCT03892902)
  • 24 Sep 2019 Idorsia Pharmaceuticals initiates a phase I trial in Healthy volunteers (In adults, In the elderly) and in Hepatically-impaired patients in Germany (PO) (NCT04024332) (EudraCT2019-002159-40)
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