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Alternative Names:
ACT-541468; DORA; Nemorexant - Idorsia Pharmaceuticals
Latest Information Update: 17 Jul 2020
Price :
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At a glance
Originator
Actelion Pharmaceuticals
Developer
Idorsia Pharmaceuticals
Class
Benzimidazoles; Chlorinated hydrocarbons; Ketones; Pyrrolidines; Sleep disorder therapies; Small molecules; Triazoles
Mechanism of Action
Orexin receptor type 1 antagonists; Orexin receptor type 2 antagonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
No
New Molecular Entity
Yes
Highest Development Phases
Phase III
Insomnia
Phase I
Sleep apnoea syndrome
Most Recent Events
23 Jul 2020
Idorsia Pharmaceuticals plans to submit a regulatory application to the US FDA for Insomnia by end of 2020
07 Jul 2020
Efficacy and adverse events data from a second phase III trial in Insomnia released by Idorsia Pharmaceuticals
26 May 2020
Idorsia Pharmaceuticals plans a phase I drug-drug interaction trial in volunteers in Germany (NCT04390334)
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