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Daridorexant - Idorsia Pharmaceuticals

Drug Profile

Daridorexant - Idorsia Pharmaceuticals

Alternative Names: ACT-541468; DORA; Nemorexant - Idorsia Pharmaceuticals

Latest Information Update: 17 Jul 2020

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At a glance

  • Originator Actelion Pharmaceuticals
  • Developer Idorsia Pharmaceuticals
  • Class Benzimidazoles; Chlorinated hydrocarbons; Ketones; Pyrrolidines; Sleep disorder therapies; Small molecules; Triazoles
  • Mechanism of Action Orexin receptor type 1 antagonists; Orexin receptor type 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Insomnia
  • Phase I Sleep apnoea syndrome

Most Recent Events

  • 23 Jul 2020 Idorsia Pharmaceuticals plans to submit a regulatory application to the US FDA for Insomnia by end of 2020
  • 07 Jul 2020 Efficacy and adverse events data from a second phase III trial in Insomnia released by Idorsia Pharmaceuticals
  • 26 May 2020 Idorsia Pharmaceuticals plans a phase I drug-drug interaction trial in volunteers in Germany (NCT04390334)
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