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Nitroxoline - Asieris Pharmaceuticals

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Drug Profile

Nitroxoline - Asieris Pharmaceuticals

Alternative Names: APL-1202; Vesique

Latest Information Update: 14 Jun 2025

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At a glance

  • Originator Johns Hopkins University
  • Developer Asieris Pharmaceuticals
  • Class Antibacterials; Antifungals; Antineoplastics; Antiprotozoals; Hydroxyquinolines; Nitroquinolines; Small molecules
  • Mechanism of Action Methionine aminopeptidase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Bladder cancer
  • Phase I Amoebiasis
  • No development reported Prostate cancer

Most Recent Events

  • 18 Apr 2025 Efficacy data from phase-I/II ANTICIPATE trail in Bladder cancer released by Asieris Pharmaceuticals
  • 31 Jan 2025 Syneos Health terminates phase I trial in for Healthy volunteers in Australia due to a business decision and development strategy (PO, Tablet) (NCT06435039)
  • 06 Jan 2025 Asieris and CDC submits IND application to US FDA for expanded-access trial

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