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MB 101 - Mustang Bio

Drug Profile

MB 101 - Mustang Bio

Alternative Names: IL13Rα2-specific CAR-T cells - Mustang Bio; MB-101 - Mustang Bio

Latest Information Update: 26 Nov 2019

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At a glance

  • Originator City of Hope National Medical Center
  • Developer City of Hope National Medical Center; National Cancer Institute (USA)
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Glioblastoma

Most Recent Events

  • 16 Oct 2019 MB 101 is still in phase I trial for Glioblastoma in USA (Intratumoural) (Intraventricualr) (NCT04003649)
  • 01 Oct 2019 Phase-I clinical trials in Glioblastoma (Combination therapy, Recurrent, Second-line therapy or greater) in USA (Intratumoural, Infusion) (NCT04003649)
  • 01 Oct 2019 Phase-I clinical trials in Glioblastoma (Monotherapy, Recurrent, Second-line therapy or greater) in USA (Intratumoural, Infusion) (NCT04003649)
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