NT 814

Drug Profile

NT 814

Latest Information Update: 13 Jun 2018

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At a glance

  • Originator GlaxoSmithKline
  • Developer KaNDy Therapeutics; NeRRe Therapeutics
  • Class Small molecules; Vascular disorder therapies
  • Mechanism of Action Neurokinin 1 receptor antagonists; Neurokinin 3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Sex hormone disorders; Vasomotor symptoms
  • Discontinued Opioid abuse

Most Recent Events

  • 07 Jun 2018 KaNDy Therapeutics plans the phase IIbSWITCH-1 trial for Vasomotor symptoms in 2018 (PO, Capsule) (NCT03596762)
  • 07 Jun 2018 Efficacy and adverse events data from the phase Ib/IIa RELENT-1 trial in Vasomotor symptoms released by KaNDy Therapeutics
  • 03 Oct 2017 Discontinued - Phase-II for Opioid abuse in United Kingdom (PO)
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