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Elinzanetant - Bayer

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Drug Profile

Elinzanetant - Bayer

Alternative Names: BAY-3427080; GSK 1144814A; GSK-1144814; NT 814

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator GlaxoSmithKline
  • Developer Bayer; GlaxoSmithKline; NeRRe Therapeutics
  • Class 2 ring heterocyclic compounds; Alcohols; Amides; Antipsychotics; Drug withdrawal therapies; Fluorinated hydrocarbons; Fluorobenzenes; Oxazines; Piperazines; Pyridines; Sleep disorder therapies; Small molecules
  • Mechanism of Action Neurokinin 1 receptor antagonists; Neurokinin 3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Vasomotor symptoms
  • Phase II Sleep disorders
  • Discontinued Opioid-related disorders; Schizophrenia

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Vasomotor-symptoms(In volunteers) in China (PO, Capsule)
  • 10 Jan 2025 Efficacy and adverse events data from a phase III OASIS 4 trial in Vasomotor symptoms released by Bayer
  • 05 Jan 2025 Phase-II clinical trials in Sleep disorders in Czech Republic (PO) (NCT06112756)

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