TAK 828

Drug Profile

TAK 828

Alternative Names: TAK-828

Latest Information Update: 16 Jun 2017

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At a glance

  • Originator Takeda
  • Class
  • Mechanism of Action Nuclear receptor subfamily 1 group F member 3 inverse agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Crohn's disease

Most Recent Events

  • 10 May 2017 Discontinued - Phase-I for Crohn's disease (In volunteers) in USA (PO) based on results of preclinical toxicology and clinical teratogenicity studies (Takeda FY2016 Q4 results, May 2017)
  • 01 Feb 2017 Takeda terminates a phase I trial in Healthy volunteers in USA (PO, Liquid) (NCT02817516)
  • 01 Jul 2016 Takeda initiates enrolment in a phase I trial for Crohn's disease (In volunteers) in USA (NCT02817516)
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