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Delolimogene mupadenorepvec - Lokon Pharma

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Drug Profile

Delolimogene mupadenorepvec - Lokon Pharma

Alternative Names: LOAd 703

Latest Information Update: 28 Sep 2023

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At a glance

  • Originator Lokon Pharma
  • Developer Lokon Pharma; Uppsala University
  • Class Antineoplastics; Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action 4-1BB ligand expression stimulants; CD40 ligand expression stimulants; Cell death stimulants; Dendritic cell stimulants; Immunologic cytotoxicity; Macrophage stimulants; Natural killer cell stimulants; T-cell receptor gene stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Biliary cancer; Colorectal cancer; Malignant melanoma; Ovarian cancer; Pancreatic cancer
  • Research Breast cancer; Sarcoma
  • No development reported B-cell lymphoma; Multiple myeloma

Most Recent Events

  • 28 Sep 2023 No recent reports of development identified for preclinical development in B-cell lymphoma in Sweden (Intratumoural, Injection)
  • 28 Sep 2023 No recent reports of development identified for preclinical development in Multiple-myeloma in Sweden (Intratumoural, Injection)
  • 30 Jul 2023 Lokon Pharma completes a phase-I/II trial in Malignant melanoma (Combination therapy) in Sweden and USA (Intratumoural) (NCT04123470)

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