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Aprocitentan - Idorsia Pharmaceuticals

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Drug Profile

Aprocitentan - Idorsia Pharmaceuticals

Alternative Names: AC 080; ACT-132577; JERAYGO; JNJ-2820; TRYVIO

Latest Information Update: 08 Jun 2026

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At a glance

  • Originator Actelion Pharmaceuticals
  • Developer Idorsia Pharmaceuticals
  • Class Amides; Antihypertensives; Cardiovascular therapies; Ethers; Halogenated hydrocarbons; Pyrimidines; Small molecules
  • Mechanism of Action Endothelin A receptor antagonists; Endothelin B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Resistant hypertension
  • Phase II Essential hypertension

Most Recent Events

  • 08 Jun 2026 Efficacy and adverse event data from a phase III PRECISION trial in Hypertension released by Idorsia Pharmaceuticals
  • 28 Apr 2026 Aprocitentan - Idorsia Pharmaceuticals is available for licensing as of 28 Apr 2026. https://www.idorsia.com/
  • 10 Nov 2025 Efficacy and adverse event data from a phase III PRECISION trial in Hypertension released by Idorsia Pharmaceuticals

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