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Mitiperstat - AstraZeneca

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Drug Profile

Mitiperstat - AstraZeneca

Alternative Names: AZD-4831

Latest Information Update: 26 Feb 2025

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; University of Cologne
  • Class Amines; Cardiotonics; Cardiovascular therapies; Chlorophenols; Heart failure therapies; Hepatoprotectants; Organic sulfur compounds; Pyrimidinones; Pyrroles; Small molecules
  • Mechanism of Action Peroxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cardiomyopathies; Pulmonary hypertension
  • Discontinued Chronic obstructive pulmonary disease; Heart failure; Non-alcoholic steatohepatitis

Most Recent Events

  • 06 Feb 2025 Discontinued - Phase-I for Heart failure (In volunteers) in United Kingdom, USA, Germany (PO) before February 2025 (AstraZeneca pipeline, February 2025)
  • 06 Feb 2025 Discontinued - Phase-II for Chronic obstructive pulmonary disease in United Kingdom, Denmark, Canada (PO) before February 2025 (AstraZeneca pipeline, February 2025)
  • 06 Feb 2025 Discontinued - Phase-II for Heart failure in Germany, Finland (PO) before February 2025 (AstraZeneca pipeline, February 2025)

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