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Favezelimab - Merck Sharp & Dohme

Drug Profile

Favezelimab - Merck Sharp & Dohme

Alternative Names: Mavezelimab - Merck Sharp & Dohme; MK-4280

Latest Information Update: 22 Jan 2024

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At a glance

  • Originator Merck Sharp & Dohme
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD223 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Haematological malignancies; Non-small cell lung cancer
  • No development reported Solid tumours

Most Recent Events

  • 09 Dec 2023 Efficacy and adverse events data from a phase I/II trial in Haematological malignancies presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)
  • 09 Dec 2023 Efficacy and adverse events data from a phase I/II trial in Haematological malignancies presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)
  • 28 Jul 2023 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease) in Canada (IV, Infusion)
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