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Olutasidenib - Forma Therapeutics

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Drug Profile

Olutasidenib - Forma Therapeutics

Alternative Names: FT 2102; IDH1-R132 Inhibitor FT-2102; REZLIDHIA

Latest Information Update: 24 Aug 2026

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At a glance

  • Originator FORMA Therapeutics
  • Developer FORMA Therapeutics; Kissei Pharmaceutical; Rigel Pharmaceuticals
  • Class Amines; Antineoplastics; Nitriles; Pyridines; Quinolines; Small molecules
  • Mechanism of Action Isocitrate dehydrogenase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute myeloid leukaemia
  • Phase II Glioma
  • Phase I/II Myelodysplastic syndromes; Solid tumours

Most Recent Events

  • 29 May 2026 Efficacy and safety data from a phase II trial in Acute myeloid leukemia presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO 2026) .
  • 27 May 2026 Phase-II clinical trials in Acute myeloid leukaemia (Second-line therapy or greater) in Japan (PO) (NCT07604064)
  • 21 May 2026 Updated efficacy data from a phase-I/II trial in Acute myeloid leukemia released by Rigel Pharmaceuticals

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