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Vafidemstat - Oryzon Genomics

Drug Profile

Vafidemstat - Oryzon Genomics

Alternative Names: ORY-2001

Latest Information Update: 31 Dec 2019

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At a glance

  • Originator Oryzon
  • Class Antidementias; Neuroprotectants; Nootropics; Small molecules
  • Mechanism of Action Lysine specific demethylase 1 inhibitors; Monoamine oxidase B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Aggression; Alzheimer's disease; Multiple sclerosis
  • No development reported Dementia; Parkinson's disease

Most Recent Events

  • 22 Oct 2019 Oryzon Genomics completes the phase IIa REIMAGINE trial in Aggression in Spain (EudraCT2018-002140-88)
  • 03 Oct 2019 Efficacy and adverse events data from the phase IIb REIMAGINE trial in Aggression (attention deficit hyperactivity disorder, autistic spectrum disorder and borderline personality disorder cohort) released by Oryzon Genomics
  • 03 Oct 2019 Oryzon Genomics plans the phase IIb COLONNADE trial in Autistic spectrum disorder
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