Efavaleukin alfa - Amgen
Alternative Names: AMG 592; IL-2 mutein Fc fusion protein - AmgenLatest Information Update: 28 Sep 2024
At a glance
- Originator Amgen
- Class Anti-inflammatories; Antirheumatics; Cytoprotectives; Immunoglobulin Fc fragments; Interleukins; Recombinant fusion proteins
- Mechanism of Action Regulatory T-lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Systemic lupus erythematosus; Ulcerative colitis
- Phase I/II Graft-versus-host disease
- No development reported Inflammation
- Discontinued Rheumatoid arthritis
Most Recent Events
- 28 Sep 2024 No recent reports of development identified for phase-I development in Inflammation(In volunteers) in United Kingdom (SC)
- 18 May 2024 Pharmacodynamics data from a phase I trial in Systemic lupus erythematous presented at the Digestive Disease Week 2024 (DDW-2024)
- 14 Oct 2023 Pooled pharmacodynamics and adverse event data from preclinical and phase I NCT03451422 studies in ulcerative colitis presented at the 31st United European Gastroenterology Week (UEGW-2023)