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Taniraleucel - Celularity

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Drug Profile

Taniraleucel - Celularity

Alternative Names: CAR19-CYNK; Cord-blood-derived-natural-killer-cells-Celgene; CYNK 001; Placental-derived natural killer cell therapy - Celularity; PNK007

Latest Information Update: 26 Dec 2024

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At a glance

  • Originator Celgene Corporation
  • Developer Celgene Corporation; Celularity; Lung Biotechnology
  • Class Antineoplastics; Cell therapies; Haematopoietic stem cells therapies; Immunotherapies; Natural killer cell therapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma; Glioma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Phase I/II COVID 2019 infections; Glioblastoma; Multiple myeloma
  • No development reported Haematological malignancies; Solid tumours

Most Recent Events

  • 12 Dec 2024 Celularity Incorporated terminates phase-I clinical trials in Acute myeloid leukaemia (Second line therapy or greater) in USA (IV) due to business reasons (NCT04310592)
  • 09 Dec 2023 Interim efficacy and adverse events data from the phase-I CYNK001AML01 trial in Acute myeloid leukaemia presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)
  • 28 Sep 2023 No recent reports of development identified for preclinical development in Haematological-malignancies in USA (IV)

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