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Dolutegravir/lamivudine - GSK

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Drug Profile

Dolutegravir/lamivudine - GSK

Alternative Names: Dovato; DTG/3TC; Lamivudine/dolutegravir

Latest Information Update: 06 Oct 2025

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At a glance

  • Originator GlaxoSmithKline
  • Developer GSK; ViiV Healthcare
  • Class 3-ring heterocyclic compounds; Amides; Antiretrovirals; Deoxyribonucleosides; Dideoxynucleosides; Oxazines; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action HIV integrase inhibitors; Nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - HIV infections
  • New Molecular Entity No

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 18 Sep 2025 Phase-III clinical trials in HIV-1 infections (Treatment-naive) in Brazil (PO) (NCT06497465)
  • 22 May 2025 ViiV Healthcare completes the phase III DANCE trial for HIV-1 infections (Treatment-naive, In adolescents, In children) in USA, South Africa, Thailand and Kenya (NCT03682848)
  • 08 Apr 2024 Registration for HIV-1 infections (In adolescents, Treatment-naive, In adults, In the elderly) in USA (PO)

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