Zilovertamab - Oncternal Therapeutics
Alternative Names: Cirmtuzumab - Oncternal Therapeutics; UC-961Latest Information Update: 28 Jul 2025
At a glance
- Originator University of California, San Diego
- Developer California Institute for Regenerative Medicine; Oncternal Therapeutics, Inc.; Pharmacyclics; UC San Diego School of Medicine; University of California, San Diego
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Receptor tyrosine kinase-like orphan receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Chronic lymphocytic leukaemia
- Phase I/II Mantle-cell lymphoma; Marginal zone B-cell lymphoma
- No development reported Endometrial cancer; HER2 negative breast cancer; Ovarian cancer; Prostate cancer
Most Recent Events
- 28 Jul 2025 No recent reports of development identified for phase-I development in Prostate-cancer(Combination therapy, Late-stage disease, Metastatic disease) in USA (Parenteral)
- 27 Jun 2025 Hoola Therapeutics acquires Zilovertamab from Oncternal Therapeutics
- 28 May 2025 No recent reports of development identified for preclinical development in Endometrial-cancer in USA (Parenteral)