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Research programme: ROR1 inhibitors - Oncternal Therapeutics, Inc.

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Drug Profile

Research programme: ROR1 inhibitors - Oncternal Therapeutics, Inc.

Alternative Names: Receptor tyrosine protein kinase like orphan receptor inhibitors - Oncternal Therapeutics, Inc.; ROR1 CAR-NK cell therapy - Oncternal Therapeutics, Inc

Latest Information Update: 28 Jul 2024

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At a glance

  • Originator University of California, San Diego
  • Developer Oncternal Therapeutics, Inc.; University of California, San Diego
  • Class Antibodies; Antineoplastics; Bispecific antibodies; CAR-NK cell therapies; Gene therapies; Immunoconjugates; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements; Receptor tyrosine kinase-like orphan receptor antagonists; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Haematological malignancies; Solid tumours

Most Recent Events

  • 28 Jul 2024 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
  • 28 May 2023 No recent reports of development identified for preclinical development in Haematological-malignancies in USA (Parenteral)
  • 23 Mar 2023 Oncternal Therapeutics has patent protection for methods of screening for antibodies that specifically bind to ROR1 in USA

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