Research programme: receptor tyrosine protein kinase like orphan receptor inhibitors

Drug Profile

Research programme: receptor tyrosine protein kinase like orphan receptor inhibitors

Alternative Names: ROR1 inhibitors - Oncternal Therapeutics, Inc.

Latest Information Update: 06 Jun 2016

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At a glance

  • Originator University of California, San Diego
  • Developer Oncternal Therapeutics, Inc.; University of California, San Diego
  • Class Antibodies; CAR-T cell therapies; Drug conjugates; Gene therapies; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Immunologic cytotoxicity; Receptor protein-tyrosine kinase antagonists; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 01 Jun 2016 Tokalas, Inc. has merged with Oncternal Therapeutics to form Oncternal Therapeutics, Inc.
  • 12 Apr 2016 University of California, San diego and Oncternal Therapeutics enter into a an exclusive worldwide license to develop and commercialise ROR1 inhibitors for Cancer
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