Research programme: anti-cancer therapeutics - Halozyme

Drug Profile

Research programme: anti-cancer therapeutics - Halozyme

Alternative Names: HTI-1511; PEG NME8058; PEG NME8062; PEG-ADA2; PEG-ADA2-E182T; PEG-ADA2-K374D; PEG-ADA2-R222Q-S265N; PEGylated adenosine deaminase 2

Latest Information Update: 26 Apr 2018

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At a glance

  • Originator Halozyme Therapeutics
  • Class Auristatins; Enzymes; Immunoconjugates
  • Mechanism of Action Adenosine deaminase stimulants; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Preclinical Cholangiocarcinoma; Chronic lymphocytic leukaemia; Colorectal cancer; Lung cancer; Pancreatic cancer
  • Discontinued Solid tumours

Most Recent Events

  • 21 Apr 2018 Pharmacodynamics data from preclinical studies in Cancer presented at the 109th Annual Meeting of the American Association for Cancer Research (AACR-2018)
  • 20 Feb 2018 Halozyme's PEG-ADA 2 is available for licensing as of 12 Apr 2018.
  • 20 Feb 2018 Discontinued - Preclinical development of HTI 1511 for Solid tumours in USA (unspecified route)
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