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Evexomostat - SynDevRx

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Drug Profile

Evexomostat - SynDevRx

Alternative Names: MetAP2 inhibitor - SynDevRx; SDX-7320

Latest Information Update: 28 Jul 2025

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At a glance

  • Originator SynDevRx, Inc
  • Developer Memorial Sloan-Kettering Cancer Center; SynDevRx, Inc
  • Class Antineoplastics; Cyclohexanes; Drug conjugates; Sesquiterpenes; Unsaturated fatty acids
  • Mechanism of Action DNA synthesis inhibitors; Methionine aminopeptidase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Triple negative breast cancer
  • Phase I/II Breast cancer
  • Preclinical Interstitial lung diseases
  • No development reported Colorectal cancer; Solid tumours

Most Recent Events

  • 28 Jul 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Monotherapy, Refractory metastatic disease) in USA (SC)
  • 28 Jun 2025 No recent reports of development identified for preclinical development in Colorectal-cancer(Metastatic disease) in USA
  • 27 Jun 2023 3798119- No significant data, only methods of trial mentioned

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