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GLPG 2451

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Drug Profile

GLPG 2451

Alternative Names: ABBV 2451; GLPG2451

Latest Information Update: 10 May 2026

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At a glance

  • Originator Cystic Fibrosis Foundation Therapeutics; Galapagos NV
  • Developer Lakefront Biotherapeutics
  • Class Antifibrotics; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cystic fibrosis

Most Recent Events

  • 08 May 2026 Galapagos NV is now called Lakefront Biotherapeutics
  • 28 May 2021 No recent reports of development identified for phase-I development in Cystic-fibrosis(Combination therapy) in Belgium (PO, Suspension)
  • 28 May 2021 No recent reports of development identified for phase-I development in Cystic-fibrosis(Combination therapy) in Bulgaria (PO, Suspension)

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