Drug Profile

Anti-CD123-anti-CD3 bispecific antibody - Janssen Research & Development

Alternative Names: Ab-178

Latest Information Update: 05 Sep 2023

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At a glance

Originator Janssen Research & Development
Class Monoclonal antibodies; Small molecules
Mechanism of Action CD3 antigen inhibitors; Interleukin-3 receptor alpha subunit antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

05 Sep 2023 Discontinued - Preclinical for Acute myeloid leukaemia in USA (Parenteral) (Janssen pharmaceuticals pipeline; September 2023)
28 May 2020 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (Parenteral)
16 Apr 2016 Preclinical trials in Cancer in USA (Parenteral) prior to April 2016

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