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Pemrametostat - GlaxoSmithKline

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Drug Profile

Pemrametostat - GlaxoSmithKline

Alternative Names: 3326595; EPZ-015938; GSK-3326595

Latest Information Update: 28 Jan 2024

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At a glance

  • Originator Epizyme
  • Developer Epizyme; GSK
  • Class Antineoplastics; Isoquinolines; Piperidines; Pyrimidines; Small molecules
  • Mechanism of Action PRMT5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer; Non-Hodgkin's lymphoma; Solid tumours
  • No development reported Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 28 Jan 2024 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma in Canada (PO, Capsule)
  • 28 Jan 2024 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma in Canada (PO, Tablet)
  • 28 Jan 2024 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma in France (PO, Capsule)

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