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Ad26 Mos4 HIV tetravalent vaccine - Janssen Vaccines and Prevention B.V

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Drug Profile

Ad26 Mos4 HIV tetravalent vaccine - Janssen Vaccines and Prevention B.V

Alternative Names: Ad26.Mos.1.Env + Ad26.Mos.2S.Env + Ad26.Mos1.Gag-Pol + Ad26.Mos2.Gag-Pol; Ad26.Mos4.HIV; Adenovirus serotype-26 mosaic-4 HIV vaccine; Adenovirus serotype-26 mosaic-4 human immunodeficiency virus vaccine; Tetravalent Ad26 Mos HIV; VAC 89220

Latest Information Update: 17 May 2024

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At a glance

  • Originator Crucell Holland
  • Developer Beth Israel Deaconess Medical Center; Janssen Vaccines and Prevention B.V
  • Class AIDS vaccines; DNA vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III HIV infections
  • Phase I/II Immunodeficiency disorders; Immunological disorders; Retrovirus infections; Sexually transmitted infections

Most Recent Events

  • 02 May 2024 anssen Vaccines & Prevention B.V withdraws prior to enrollment a phase I trial for HIV infections in Thailand (IM, Injection), since protocol was changed during development (NCT05769569)
  • 12 Jan 2024 US Army Medical Research and Development Command and Janssen Vaccines and Prevention plans a phase I trial for HIV infection (Prevention) in January 2024 in Uganda (IM) (NCT06205056)
  • 22 Nov 2023 Janssen Vaccines & Prevention B.V. completes the phase I/II IPCAVD-012 trial in HIV infections (Prevention) in Kenya, Rwanda and the US (NCT02935686)

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