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Endoxifen - Atossa Therapeutics

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Drug Profile

Endoxifen - Atossa Therapeutics

Alternative Names: (Z)-endoxifen

Latest Information Update: 05 Aug 2025

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At a glance

  • Originator Atossa Genetics
  • Developer Atossa Therapeutics; Weill Cornell Medicine
  • Class Antineoplastics; Methylamines; Phenyl ethers; Small molecules; Stilbenes
  • Mechanism of Action Estrogen receptor antagonists; Selective estrogen receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Breast cancer; Ductal carcinoma; HER2 negative breast cancer
  • Preclinical Triple negative breast cancer
  • No development reported Gynaecomastia; Ovarian cancer

Most Recent Events

  • 05 Aug 2025 Atossa Therapeutics plans a pre-IND meeting with the US FDA for endoxifen in ER+/HER2- Breast cancer
  • 31 Jul 2025 Atossa Therapeutics received positive feedback from US FDA for endoxifen in ER+/HER2- Breast cancer
  • 29 Jul 2025 Atossa Therapeutics announces intention to submit IND to US FDA for ER+/HER- Breast cancer in fourth quarter of 2025

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