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Endoxifen - Atossa Therapeutics

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Drug Profile

Endoxifen - Atossa Therapeutics

Alternative Names: (Z)-endoxifen; Z-endoxifen - Atossa Therapeutics

Latest Information Update: 10 Feb 2026

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At a glance

  • Originator Atossa Genetics
  • Developer Atossa Therapeutics; Weill Cornell Medicine
  • Class Antineoplastics; Methylamines; Phenyl ethers; Small molecules; Stilbenes
  • Mechanism of Action Estrogen receptor antagonists; Selective estrogen receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity No

Highest Development Phases

  • Phase II Breast cancer; Ductal carcinoma; HER2 negative breast cancer
  • Preclinical Triple negative breast cancer
  • Research Duchenne muscular dystrophy
  • No development reported Gynaecomastia; Ovarian cancer

Most Recent Events

  • 05 Feb 2026 Atossa anticipates receiving a Rare Pediatric Disease Priority Review Voucher for Endoxifen upon FDA approval
  • 16 Jan 2026 Endoxifen - Atossa Therapeutics receives Orphan Drug status for Duchenne muscular dystrophy in USA
  • 06 Jan 2026 The US FDA approves IND application for Atossa Therapeutics in Breast cancer (Metastatic disease)

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