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Nicotinamide riboside - Niagen Bioscience

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Drug Profile

Nicotinamide riboside - Niagen Bioscience

Alternative Names: NIAGEN; Niagen IV - Niagen Bioscience; Niagen® Plus - Niagen Bioscience; nicotinamide riboside chloride; Nicotinamide-beta-riboside; Nicotinamide-ribonucleoside; Nicotinamide-ribose; NRC; SRT-647; Tru Niagen® - Niagen Bioscience

Latest Information Update: 02 Dec 2025

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At a glance

  • Originator Cornell University; Dartmouth College; Washington University
  • Developer Ecole Polytechnique Federale de Lausanne.; Emory University; Haukeland University Hospital; National Institutes of Health (USA); Niagen Bioscience; University of Cambridge; University of Iowa; Washington University
  • Class Amides; Analgesics; Antivirals; Nicotinic acids; Pyridines; Small molecules; Vitamins
  • Mechanism of Action Nicotinamide adenine dinucleotide modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ataxia telangiectasia
  • New Molecular Entity No

Highest Development Phases

  • Phase III Parkinson's disease
  • Preclinical Ataxia telangiectasia
  • Discontinued Alzheimer's disease; Cockayne syndrome; COVID 2019 infections; Heart failure; Mitochondrial myopathies; Pain; Retinal disorders

Most Recent Events

  • 01 Oct 2025 ChromaDex initiates enrolment in a phase I pharmacodynamics trial in Healthy volunteers in USA (SC, IM) (NCT07251608)
  • 13 Aug 2025 Phase-III clinical trials in Parkinson's disease in Norway (PO) (NCT03568968)
  • 20 Mar 2025 Niagen Bioscience has patent protection for nicotinamide riboside (NR) salt forms and derivatives in USA .

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